- Original Article
- Gastroenterology
- Influence of proton pump inhibitor therapy on intestinal inflammation assessed by fecal calprotectin in pediatric patients
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Su Yeong Kim, Na Mi Lee, Sin Weon Yun, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Dae Yong Yi
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Clin Exp Pediatr. 2019;62(10):400-404. Published online July 3, 2019
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Background: An increase in the numbers of patients with gastrointestinal symptoms has recently been observed.
Purpose: To investigate the effects of proton pump inhibitor (PPI) therapy on intestinal inflammation in children and adolescents as confirmed by clinical manifestations and objectively assessed by fecal calprotectin (FC) level measurement.
Methods: Consecutive children (aged 3–18 years) who presented with gastrointestinal symptoms and were treated with... |
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- Neuroprotective effects of mild hypoxia in organotypic hippocampal slice cultures
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Seh Hyun Kim, Woo Soon Lee, Na Mi Lee, Soo Ahn Chae, Sin Weon Yun
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Clin Exp Pediatr. 2015;58(4):142-147. Published online April 22, 2015
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Purpose The aim of this study was to investigate the potential effects of mild hypoxia in the mature and immature brain. MethodsWe prepared organotypic slice cultures of the hippocampus and used hippocampal tissue cultures at 7 and 14 days in vitro (DIV) to represent the immature and mature brain, respectively. Tissue cultures were exposed to 10% oxygen for 60 minutes. Twenty-four hours... |
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- Review Article
- Congenital heart disease in the newborn requiring early intervention
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Sin Weon Yun
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Clin Exp Pediatr. 2011;54(5):183-191. Published online May 31, 2011
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Although antenatal diagnostic technique has considerably improved, precise detection and proper management of the neonate with congenital heart disease (CHD) is always a great concern to pediatricians. Congenital cardiac malformations vary from benign to serious conditions such as complete transposition of the great arteries (TGA), critical pulmonary and aortic valvular stenosis/atresia, hypoplastic left heart syndrome (HLHS), obstructed total anomalous pulmonary... |
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- Original Article
- Epidemiologic and clinical features in children with acute lower respiratory
tract infection caused by human metapneumovirus in 2006-2007
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Gwi Ok Park, Ji Hyun Kim, Jae Hee Lee, Jung Ju Lee, Sin Weon Yun, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byoung Hoon Yoo,, Mi Kyung Lee, Soo Ahn Chae
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Clin Exp Pediatr. 2009;52(3):330-338. Published online March 15, 2009
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Purpose : The causes of acute lower respiratory tract infection (ALRTI) are mostly attributable to viral infection, including respiratory syncytial virus (RSV), parainfluenza virus (PIV), influenza virus A/B (IFV A/B), or adenovirus (ADV). Several Korean studies reported human metapneumovirus (hMPV) as a common pathogen of ALRTI. However, studies on seasonal distribution and clinical differences relative to other viruses are insufficient,... |
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- Case Report
- Partial trisomy of chromosome 18q11.2-q12: A case report
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Ah Ra Cho, Hye Ryoun Kim, Mi Kyung Lee, Sin Weon Yun, Jung Ju Lee
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Clin Exp Pediatr. 2009;52(10):1171-1174. Published online October 15, 2009
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Edwards syndrome, also called trisomy 18, is one of the most common autosomal anomalies. The survival rate of patients with Edwards syndrome is very low and its characteristic findings include cardiac malformations, mental retardation, growth retardation, specific craniofacial anomalies, clenched hands, rocker-bottom feet, and omphalocele. Compared with the classic Edwards syndrome, the symptom of partial duplication of chromosome 18 is... |
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- A case of herpes zoster in a 4-month-old infant
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Ji Hyun Kim, Jung Ju Lee, Sin Weon Yun, Soo Ahn Chae, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byoung Hoon Yoo
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Clin Exp Pediatr. 2008;51(12):1368-1371. Published online December 15, 2008
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Herpes zoster in infancy is very rare but can be developed following intrauterine or postnatal exposure to varicella zoster virus. We report a case of herpes zoster in a 4-month-old male infant. He had no prior history of primary varicella or varicella vaccination. His mother had no history of varicella infection and no contact history with varicella during pregnancy. He... |
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- Original Article
- Clinical significance of serum vascular endothelial growth factor in Kawasaki disease
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Ho Seok Lee, Sin Weon Yun, Young Soo Jung, Soo Ahn Chae, In Seok Lim, Dong Keun Lee, Eung Sang Choi, Byung Hoon Yoo, Mi Kyung Lee
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Clin Exp Pediatr. 2007;50(10):995-1004. Published online October 15, 2007
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Purpose : Kawasaki disease is a systemic vasculitis, leading cause of pediatric acquired heart disease. Vascular endothelial growth factor (VEGF) has functions as vascular permeability factor, plays an important role in coronary artery lesion (CAL). We studied the clinical significance of serum VEGF in Kawasaki disease.
Methods : Kawasaki group was 49 patients, and control group was 15 patients. Diagnosis followed... |
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- Changes of Lipid and Lipoprotein Compositions in Kawasaki Disease and its Impact on Cardiac Complications
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Sin Weon Yun, Ho Seok Lee, Dong Woon Kim, Kang Won Rhee, Young Soo Jung
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Clin Exp Pediatr. 2005;48(12):1370-1377. Published online December 15, 2005
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Purpose : Delineation of serum lipid and lipoprotein values in children after Kawasaki disease(KD) is important because of the predilection of this disease for the coronary arteries.
Methods : The KD group was composed of 51 patients who were hospitalized from Jan. 2002 to Dec. 2003. Control was 25 patients with non-KD febrile illness. The levels of total lipid, phospholipid,... |
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- The Significance of Serologic Allergy Tests in Children with Recurrent Pneumonia
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Yoon Hee Sim, Sin Weon Yun, Soo Ahn Chae, Dong Keun Lee
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Clin Exp Pediatr. 2004;47(6):634-640. Published online June 15, 2004
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Purpose : Pneumonia is one of the most common respiratory diseases in hospitalized children, and often recurs. It has been reported that asthma is one of the significant contributing factors to recurrent pneumonia. On the basis of similarities between asthma and recurrent pneumonia, we intended to evaluate the influence of allergy on recurrent pneumonia.
Methods : Seventy one children with... |
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- Case Report
- Pseudoaneurysm after Renal Biopsy; Angigraphic Diagnosis and Treatment by Superselective Embolization
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Sin Weon Yun, Keun Seop Jung, In Seok Lim, Chul Ha Kim, Dong Keun Lee, Byeong Heun You, Hyung Jin Shim, Young Ku Kim
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Clin Exp Pediatr. 1995;38(3):417-421. Published online March 15, 1995
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The use of superselective embolization was assessed as a treatment for bleeding from arteriovenous fistulas and pseudoaneurysm after renal biopsy procedure. But unless it is sufficiently selective, the procedure results in loss of significant amount of renal parenchyme. We experienced one case of renal arterial pseudoaneurysm, which happened at 5days after percutaneous renal biopsy. Diagnosis of pseudoaneurysm was made by... |
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